Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling - CRCL-Apoptose, cancer et développement
Journal Articles Cell Reports Year : 2023

Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling

Benjamin Ducarouge
  • Function : Author

Abstract

Highlights d Netrin-1 is upregulated in metastatic pancreatic cancer d Hepatic stellate cell-secreted retinoic acid upregulates Netrin-1 in the liver d Netrin-1 on extracellular vesicles preconditions the metastatic niche

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Cancer
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Dates and versions

hal-04382892 , version 1 (09-01-2024)

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Crissy Dudgeon, Anthony Casabianca, Chris Harris, Charline Ogier, Mélanie Bellina, et al.. Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling. Cell Reports, 2023, 42, ⟨10.1016/j.celrep.2023.113369⟩. ⟨hal-04382892⟩
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